I can’t believe it took me this long to find centrophenoxine. It’s the single most effective, accessible, versatile and effective nootropic I’ve come across. It’s boosted my intelligence, unquestionably, and in some very interesting ways.
Not only that, but it turns out that it has powerful anti-aging effects that benefit you beyond the short-term boost that it can give you on a day-to-day basis.
When it comes to nootropics, it seems there are two types: the safe ones, and the super-effective ones. After all, there are lots of dietary/lifestyles ways to improve your brain function, all of which I try to use in my daily life, such as:
- Vitamin D3
- Fish Oils and other Omega-3 sources
- A healthy diet in general
That’s all well and good, but these things are long-term health choices, not exactly something you can use to get an extra boost — an extra advantage in brain power. And even drugs as mild as caffeine come with their downsides.
On the flip side there are all kinds of powerful nootropics out there that can interact in bad ways, or which carry a health risk, or which simply don’t work at all.
Isn’t there something better?
Centrophenoxine — General information
Say Hello to Centrophenoxine
Centrophenoxine is a derivative of the well-researched brain-supplement DMAE, and it’s marketed under the trade name Lucidril. You can buy centrophenoxine powders perfectly legally, and they’re available off sites like Amazon (but the quality and concentration can vary pretty widely!)
It’s also known as meclofenoxate. This stuff is originally marketed as a drug (to treat Alzheimer’s, among other things), but we’re looking at it as a nootropic — an extremely effective one.
Centrophenoxine increases the amount of choline available to your brain, and for that reason it stacks very well with some commonly used nootropics from the racetam family, like piracetam and pramiracetam, which increase acetylcholine activity.
The difference is that centrophenoxine actually passes the blood-brain barrier and can increase the amount of acetylcholine manufactured in your brain. So while it’s not technically a choline source (as is sometimes claimed!), it functionally performs the same job as choline supplements: feeding acetylcholine to the brain.
Remember that bit about it passing the blood-brain barrier! That’s going to come back later.
Finally, centrophenoxine has well-established anti-oxidant properties, reducing free-radicals in the brain that can damage neurons.
Centrophenoxine Benefits and Effects
This stuff basically makes you feel like your memory has been enlarged. It’s just easier to access knowledge that’s already in your brain, and makes the understanding of new ideas and facts much easier.
If your brain is the CPU, and the raw total information your brain cells can store is like a computer’s memory, then centrophenoxine is like a boost to your RAM. You’re just able to handle more at once. This is a kind of “functional smarts” that’s incredibly useful and broadly applicable.
Centrophenoxine is kind of like an across-the-board boost for your overall brain power.
I’ve seen a lot of different claims for this supplement (it seems to be popular with those who know their stuff!). But the only benefits that I feel comfortable talking about are the ones that are:
- A) Backed up by studies, and
- B) Backed up by my own personal experience.
So with that said, here are the main centrophenoxine benefits:
- Memory boost
- Relief of mild social anxiety
- Relief of mild depression
- Increased libido
- Lucid dreaming
You might be thinking, huh? Libido? Mood? Let me explain.
Recall that bit about the blood-brain barrier? Well that’s where the other amazing effect of centrophenoxine comes in.
Have you heard of lipofuscin? It’s in your body right now, and it’s making you age by the minute. Basically, lipofuscin is a by-product of metabolism. You can’t live and function without your cells producing some of this by-product. Basically it’s garbage generated by your cells creating energy for daily use.
This cellular garbage accumulates over time and tends to bond to various cellular molecules and build up in certain areas.
Lipofuscin, in fact, is the main cause of “liver spots,” those brown blotches older people get on their hands and sometimes their faces. It also causes macular degeneration, one of the leading causes of blindness in the elderly. In general, this is just a bunch of unnecessary muck gumming up your body from head to toe.
Here’s where centrophenoxine comes in. Essentially, it has the ability to “liberate” lipofuscin from where it has bonded with your living tissue, allowing the body to clean it up and eliminate it normally, like it does with most daily toxins.
This has an anti-aging effect on the whole body.
However, since centrophenoxine also operates within the brain itself (and not just in the bloodstream), it can carry out this “cleaning” function inside the brain. In fact this effect is so powerful that research has shown that it can even reverse the damage done by excessive alcohol use.
So it’s this anti-aging, generally “cleaning” effect that, over the medium term, can improve your mood and your libido, in addition to its already fantastic short-term brain- and memory-enhancing characteristics.
I started using centrophenoxine for studying, found it worked great, and kept it in my nootropic rotation for its other fantastic health and mind benefits.
It can’t be all good, can it? CAN IT?
So in my experience, this stuff can’t be beat. I was sort of wincing when I first read about it because I assumed there must be some pretty powerful side-effects for something that was such a seemingly silver bullet.
Well, here’s the deal. The family of supplements that centrophenoxine comes from (DMAE), is very well-understood. They’ve been researching it for five decades now. Basically, everything bad that could happen from this stuff has already been discovered. And it’s pretty mild.
There is a risk of:
- Tolerance: basically, over time, it can slowly become less effective, so cycle it in and out of your stack every few weeks, and you should be good.
- Potential toxicity: basically, don’t take triple dosages or whatever. That’s true of anything you put into your body of course. This should go without saying.
- Mild side-effects: basically the same laundry list that you see with any supplement. The following very vague side-effects (which I never noticed at all): headache, nausea, dizziness. These are rarely reported, and like I said, I never felt them at all.
- Counter-indicated for people with high blood pressure or convulsive disorders. If you have HBP, use centrophenoxine with care, or not at all. If you have seizures, you’re out of luck too.
And that’s about it! So centrophenoxine supplements are basically safe, if you take sensible precautions. They are the safest, easiest memory enhancers I’ve ever come across. If you are looking for pills that make you smarter, but you want to do it safely and effectively, and you want to make your skin healthier and your body cleaner… you are looking for the centrophenoxine experience.
How to take it
Centrophenoxine usage 101 for beginners
Centrophenoxine is pretty easy to store. It has a long shelf life. If you store it at room temperature, it will stay effective for two months. Much longer if you refrigerate it, so just do that and you will certainly run out and can order more, long before it expires. This is helpful because it allows you to buy in bulk to save money.
A typical, effective recommended dosage is between 300 mg and 1000 mg a day. If you are taking tablets, just make sure you read carefully what the dose is. If you buy centrophenoxine powder, it’s just a bit more work to set up your dose each day (you can mix it with water or juice), but the upside is that you can precisely choose your daily dose, and slowly adjust it over time to see what works best for you. Start with 300 mg a day and increase it as desired, up to 1000 mg. Above that is not recommended.
One thing to note is that centrophenoxine tends to give you a low-level but very noticeable energy boost throughout the day (one of the best effects!). So take your doses in the morning or early afternoon. You don’t want it keeping you up all night (or maybe you do, haha).
Pills are super easy to take. Just swallow them with water. Generally it’s best to take centrophenoxine on an empty stomach since it is water soluble. That allows it to more easily enter the bloodstream and there’s no risk of stomach ache. One note: some people report irritation under the tongue if taken sublingually. I don’t know why you would want to do that with a slow-acting compound like this, but in any case, don’t do it. Just mix powder with water, or swallow pills with water.
Centrophenoxine vs other Choline Sources
Nootropic users know that choline is an absolute must when it comes to boosting brain power. So the real question is, where to get your choline enhancement?
First of all, choline is readily available in dietary form in foods like fish and eggs. A healthy diet is absolutely indispensible.
But, assuming you are already on your game, diet-wise, how can you push things to the next level with your brain power, via choline?
Well, there are a lot of supplements out there as choices. Personally, I like centrophenoxine for a couple of reasons.
- Readily available to the brain, by passing the blood-brain barrier
- Anti-aging effects (and even makes your skin looks better)
Basically, centrophenoxine is like a super-choline source. Eat your fish, eat your eggs… and take your centrophenoxine, is my feeling.
But everyone is different. This is the supplement you want to be taking properly, long-term, along with racetams. So find what works best for you. Alpha GPC and CDP Choline are options that have worked well for many people. At the very least, it’s best to give them all a try, and vary your stacks and your dosages according to your results. All bodies are different and there is no single one answer for every human being out there.
Where to buy centrophenoxine
Don’t sell yourself short
It’s not available at GNC or Vitamin Shoppe, unfortunately. But there are several vendors on Amazon and eBay that will sell you centrophenoxine in powder or capsule form. You can find centrophenoxine for sale on several other independent retailers sites, too. Be sure to shop around and check out the reviews. The dosages and concentrations tend to vary widely.
Typically you can expect to spend about $ 20 USD for 50 grams of centrophenoxine. If you are using 500 mg a day (pretty typical), that’s enough for about three months, making it a very affordable supplement.
Both powder and capsules can work equally well. It’s really just a matter of personal preference, price, and how much you trust the vendor. Be sure to do the math on the actual dosage vs price, as some powders may contain quite a bit of filler material.